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Tepezza (teprotumumab)

What is Tepezza?

Tepezza (teprotumumab) is a monoclonal antibody medication which was FDA-approved in the US in the spring of 2020. Tepezza is the only medication which has been shown to permanently improve inflammation, proptosis, and double vision in patients with thyroid eye disease.

active thyroid eye disease

patient with active, inflammatory TED

Who is a candidate for Tepezza?

Currently, patients who have active thyroid eye disease and meet specific clinical criteria (clinical activity score >4) are a candidate for the drug. Tepezza may work better the earlier you start the drug, so do not delay getting a formal evaluation!

What are common side effects?

Tepezza is not for patients with inflammatory bowel disease (Crohn’s or ulcerative colitis). The most common side effects included high blood sugar, muscle spasm, tinnitus (ringing ears), and gastrointestinal upset.

Alternative Medicine
Dr. Deepak Ramesh treating a patient with thyroid eye disease

before and after medical treatment alone for TED

What is Dr. Ramesh's experience with Tepezza?

Dr. Ramesh was involved in the initial research for this medication prior to FDA approval, both in this time at UCLA as well as in his private practice at Wills Eye Hospital, and has extensive experience in treating patients with this drug both locally and in collaboration with other physicians for patients who travel from a distance.

Dr. Ramesh was also selected as one of the world experts in administration and treatment of thyroid eye disease with Tepezza by Horizon Therapeutics, the pharmaceutical company who manufactures Tepezza. In this role, Dr. Ramesh educates surgeons, endocrinologists, and primary eye care providers in the early diagnosis and state-of-the-art management of thyroid eye disease.

Are there ongoing research trials?

Yes, Dr. Ramesh is involved in ongoing research projects with Tepezza. Please contact our office to see if you are qualified for any research trials.

Tepezza research
Tepezza insurance

Does insurance cover Tepezza?

Tepezza can be covered by health insurance for many patients. This depends on your medical history, severity of disease, and health insurance. Please contact our office to see if medical insurance would cover Tepezza for you.


35 Clyde Road, #104

Somerset, NJ 08873

phone: 609-608-0142

fax: 855-644-0469