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What is Tepezza?

Patient after 2 of 8 doses of Tepezza

Who is a candidate for Tepezza?

Currently, patients who have active thyroid eye disease and meet specific clinical criteria (clinical activity score >4) are a candidate for the drug. Tepezza may work better the earlier you start the drug, so do not delay getting a formal evaluation! However, Dr. Ramesh is part of ongoing studies for patients who have chronic thyroid eye disease (meaning they have had the disease for > 2 years). Patients may still benefit from being treated even if they have had disease for years. We encourage an evaluation with Dr. Ramesh to see if Tepezza is right for you.

What are common side effects?

Tepezza is not for patients with inflammatory bowel disease (Crohn’s or ulcerative colitis). The most common side effects included high blood sugar, muscle spasm, tinnitus (ringing ears), and gastrointestinal upset. 90% of patients who start Tepezza are able to finish the treatment without having to stop due to other side effects. Dr. Ramesh is also experienced in alternate dosing regimens to minimize the risk of side effects.

Patient after 4 of 8 doses of Tepezza

What is Dr. Ramesh's experience with Tepezza?

Dr. Ramesh was involved in the initial research for this medication prior to FDA approval, both in this time at UCLA as well as in his private practice at Wills Eye Hospital, and has extensive experience in treating patients with this drug both locally and in collaboration with other physicians for patients who travel from a distance.

Dr. Ramesh was also selected as one of the world experts in administration and treatment of thyroid eye disease with Tepezza by Horizon Therapeutics, the pharmaceutical company who manufactures Tepezza. In this role, Dr. Ramesh educates surgeons, endocrinologists, and primary eye care providers in the early diagnosis and state-of-the-art management of thyroid eye disease.

Patient with reduction in periorbital fat after just 1 of 8 doses of Tepezza

Before & After

Before and after medical treatment alone for TED.

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